About

A scientist shaped by three continents.

Raphael S. Onuku is a Nigerian medicinal chemist and PhD candidate at the University of Michigan.

Raphael Onuku presenting medicinal chemistry research at a scientific poster session
Sharing medicinal chemistry research
Raphael Onuku at the University of Michigan College of Pharmacy
University of Michigan
Raphael Onuku in a laboratory coat at Taipei Medical University
Taipei Medical University

Scientific path

My scientific path began in pharmacy at the University of Nigeria, where an undergraduate project on HIV-1 protease introduced me to structure-based computational drug discovery. That experience established a question that still guides my work, how can molecular models become better experimental decisions?

At Taipei Medical University, I trained in medicinal chemistry, organic synthesis, and molecular simulation while developing celecoxib-based histone deacetylase inhibitors for glioblastoma. I completed the degree as a Taiwan Government Scholar and received the 2023 Outstanding Graduate Student Award.

A predoctoral internship at Academia Sinica expanded my computational work into peptide self-assembly. I am now completing doctoral training in Medicinal Chemistry at the University of Michigan, where I integrate peptide chemistry with computational design to develop anti-infective therapeutic candidates.

What drives the work

I am interested in scientific problems that require movement between disciplines. My work may begin with a molecular structure, continue through a simulation, become a synthesized peptide, and return as biological data that changes the original hypothesis.

My long-term goal is to lead translational anti-infective drug-discovery programs that connect medicinal chemistry, peptide science, computational design, and experimental pharmacology.

Recognition

Selected awards

Potential Made Possible Scholarship, CEW+ Scholarship Program, 2026

Rackham Conference Travel Grant, University of Michigan, 2024

Outstanding Graduate Student Award, Taiwan, 2023

Eugene and Shirley Cordes Scholarship, University of Michigan, 2023

Falling Walls Lab Taipei Award Winner, 2022

Professional societies

Sigma Xi, The Scientific Research Honor Society

Rho Chi Society, Alpha Chapter