About

A scientist shaped by three continents.

Raphael Onuku is a Nigerian medicinal chemist and PhD candidate at the University of Michigan.

Raphael Onuku presenting medicinal chemistry research at a scientific poster session
Sharing medicinal chemistry research
Raphael Onuku at the University of Michigan College of Pharmacy
University of Michigan
Raphael Onuku in a laboratory coat at Taipei Medical University
Taipei Medical University

Scientific journey

Knowledge carried across continents

Three institutions mark a continuing path from pharmacy to medicinal chemistry and peptide science.

Raphael Onuku's scientific journey A visual path connecting the University of Nigeria, Taipei Medical University, and the University of Michigan. Nigeria Taiwan United States
  1. 01University of NigeriaPharmacy and computational discovery
  2. 02Taipei Medical UniversityMedicinal chemistry and molecular simulation
  3. 03University of MichiganPeptide science and anti-infective discovery

Scientific path

My scientific path began in pharmacy at the University of Nigeria, where an undergraduate project on HIV-1 protease introduced me to structure-based computational drug discovery. That experience established a question that still guides my work, how can molecular models become better experimental decisions?

At Taipei Medical University, I trained in medicinal chemistry, organic synthesis, and molecular simulation while developing celecoxib-based histone deacetylase inhibitors for glioblastoma. I completed the degree as a Taiwan Government Scholar and received the 2023 Outstanding Graduate Student Award.

A predoctoral internship at Academia Sinica expanded my computational work into peptide self-assembly. I am now completing doctoral training in Medicinal Chemistry at the University of Michigan, where I integrate peptide chemistry with computational design to develop anti-infective therapeutic candidates.

What drives the work

I am interested in scientific problems that require movement between disciplines. My work may begin with a molecular structure, continue through a simulation, become a synthesized peptide, and return as biological data that changes the original hypothesis.

My long-term goal is to lead translational anti-infective drug-discovery programs that connect medicinal chemistry, peptide science, computational design, and experimental pharmacology.

Recognition

Selected awards

Potential Made Possible ScholarshipCEW+ Scholarship Program

Eugene and Shirley Cordes ScholarshipDepartment of Medicinal Chemistry, University of Michigan

Outstanding Graduate Student AwardMinistry of Education and Ministry of Foreign Affairs, Republic of China (Taiwan)

Falling Walls Lab Taipei Award Winner“Breaking the Wall of Multi-Drug-Resistant Malaria”

Taiwan Government ScholarshipMinistry of Education (MOE), Republic of China (Taiwan)

Professional societies

Sigma Xi, The Scientific Research Honor Society

Rho Chi Society, Alpha Chapter